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Derailed Intraneuronal Signalling Drives Pathogenesis in Sporadic and Familial Alzheimer's Disease

Although a wide variety of genetic and nongenetic Alzheimer's disease (AD) risk factors have been identified, their role in onset and/or progression of neuronal degeneration remains elusive. Systematic analysis of AD risk factors revealed that perturbations of intraneuronal signalling pathways...

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Detalles Bibliográficos
Autores principales: Van Dooren, Tom, Princen, Katrien, De Witte, Koen, Griffioen, Gerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160617/
https://www.ncbi.nlm.nih.gov/pubmed/25243118
http://dx.doi.org/10.1155/2014/167024