Highly efficient generation of induced neurons from human fibroblasts that survive transplantation into the adult rat brain

Induced neurons (iNs) offer a novel source of human neurons that can be explored for applications of disease modelling, diagnostics, drug screening and cell replacement therapy. Here we present a protocol for highly efficient generation of functional iNs from fetal human fibroblasts, and also demons...

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Detalles Bibliográficos
Autores principales: Pereira, Maria, Pfisterer, Ulrich, Rylander, Daniella, Torper, Olof, Lau, Shong, Lundblad, Martin, Grealish, Shane, Parmar, Malin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160709/
https://www.ncbi.nlm.nih.gov/pubmed/25208484
http://dx.doi.org/10.1038/srep06330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160709/
https://www.ncbi.nlm.nih.gov/pubmed/25208484
http://dx.doi.org/10.1038/srep06330

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