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Highly efficient generation of induced neurons from human fibroblasts that survive transplantation into the adult rat brain
Induced neurons (iNs) offer a novel source of human neurons that can be explored for applications of disease modelling, diagnostics, drug screening and cell replacement therapy. Here we present a protocol for highly efficient generation of functional iNs from fetal human fibroblasts, and also demons...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160709/ https://www.ncbi.nlm.nih.gov/pubmed/25208484 http://dx.doi.org/10.1038/srep06330 |