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Overexpression of p49/STRAP alters cellular cytoskeletal structure and gross anatomy in mice

BACKGROUND: The protein p49/STRAP (SRFBP1) is a transcription cofactor of serum response factor (SRF) which regulates cytoskeletal and muscle-specific genes. RESULTS: Two conserved domains were found in the p49/STRAP protein. The SRF-binding domain was at its N-terminus and was highly conserved amon...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaomin, Azhar, Gohar, Rogers, Steven C, Foster, Stephen R, Luo, Shaoke, Wei, Jeanne Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160719/
https://www.ncbi.nlm.nih.gov/pubmed/25183317
http://dx.doi.org/10.1186/1471-2121-15-32