Subcellular Localization of Dystrophin Isoforms in Cardiomyocytes and Phenotypic Analysis of Dystrophin-deficient Mice Reveal Cardiac Myopathy is Predominantly Caused by a Deficiency in Full-length Dystrophin

Duchenne muscular dystrophy (DMD) is an X-linked recessive progressive muscle degenerative disorder that causes dilated cardiomyopathy in the second decade of life in affected males. Dystrophin, the gene responsible for DMD, encodes full-length dystrophin and various short dystrophin isoforms. In th...

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Detalles Bibliográficos
Autores principales: Masubuchi, Nami, Shidoh, Yuichi, Kondo, Shunzo, Takatoh, Jun, Hanaoka, Kazunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2013
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160940/
https://www.ncbi.nlm.nih.gov/pubmed/23903056
http://dx.doi.org/10.1538/expanim.62.211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160940/
https://www.ncbi.nlm.nih.gov/pubmed/23903056
http://dx.doi.org/10.1538/expanim.62.211

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