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Regulation of Apelin and Its Receptor Expression in Adipose Tissues of Obesity Rats with Hypertension and Cultured 3T3-L1 Adipocytes

The apelin/APJ system has been implicated in obesity-related hypertension. We investigated the mechanism responsible for the pathogenesis of obesity-related hypertension with a special focus on the crosstalk between AngII/its type 1 receptor (AT1R) signaling and apelin/APJ expression. Sprague-Dawley...

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Detalles Bibliográficos
Autores principales: Wu, Hongxian, Cheng, Xian Wu, Hao, Changning, Zhang, Zhi, Yao, Huali, Murohara, Toyoaki, Dai, Qiuyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160987/
https://www.ncbi.nlm.nih.gov/pubmed/24770651
http://dx.doi.org/10.1538/expanim.63.257