Epsin deficiency impairs endocytosis by stalling the actin-dependent invagination of endocytic clathrin-coated pits

Epsin is an evolutionarily conserved endocytic clathrin adaptor whose most critical function(s) in clathrin coat dynamics remain(s) elusive. To elucidate such function(s), we generated embryonic fibroblasts from conditional epsin triple KO mice. Triple KO cells displayed a dramatic cell division def...

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Detalles Bibliográficos
Autores principales: Messa, Mirko, Fernández-Busnadiego, Rubén, Sun, Elizabeth Wen, Chen, Hong, Czapla, Heather, Wrasman, Kristie, Wu, Yumei, Ko, Genevieve, Ross, Theodora, Wendland, Beverly, De Camilli, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161027/
https://www.ncbi.nlm.nih.gov/pubmed/25122462
http://dx.doi.org/10.7554/eLife.03311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161027/
https://www.ncbi.nlm.nih.gov/pubmed/25122462
http://dx.doi.org/10.7554/eLife.03311

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