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Simultaneous mapping of membrane voltage and calcium in zebrafish heart in vivo reveals chamber-specific developmental transitions in ionic currents

The cardiac action potential (AP) and the consequent cytosolic Ca(2+) transient are key indicators of cardiac function. Natural developmental processes, as well as many drugs and pathologies change the waveform, propagation, or variability (between cells or over time) of these parameters. Here we ap...

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Detalles Bibliográficos
Autores principales: Hou, Jennifer H., Kralj, Joel M., Douglass, Adam D., Engert, Florian, Cohen, Adam E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161048/
https://www.ncbi.nlm.nih.gov/pubmed/25309445
http://dx.doi.org/10.3389/fphys.2014.00344