Mouse Genome Engineering Using Designer Nucleases

Transgenic mice carrying site-specific genome modifications (knockout, knock-in) are of vital importance for dissecting complex biological systems as well as for modeling human diseases and testing therapeutic strategies. Recent advances in the use of designer nucleases such as zinc finger nucleases...

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Detalles Bibliográficos
Autores principales: Hermann, Mario, Cermak, Tomas, Voytas, Daniel F., Pelczar, Pawel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2014
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161146/
https://www.ncbi.nlm.nih.gov/pubmed/24747757
http://dx.doi.org/10.3791/50930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161146/
https://www.ncbi.nlm.nih.gov/pubmed/24747757
http://dx.doi.org/10.3791/50930

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