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Mouse liver repopulation with hepatocytes generated from human fibroblasts

Human induced pluripotent stem cells (iPSCs) promise to revolutionize research and therapy of liver diseases by providing a source of hepatocytes for autologous cell therapy and disease modeling. However, despite progress in advancing the differentiation of iPSCs into hepatocytes (iPSC-Heps) in vitr...

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Detalles Bibliográficos
Autores principales: Zhu, Saiyong, Rezvani, Milad, Harbell, Jack, Mattis, Aras N., Wolfe, Alan R., Benet, Leslie Z., Willenbring, Holger, Ding, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161230/
https://www.ncbi.nlm.nih.gov/pubmed/24572354
http://dx.doi.org/10.1038/nature13020