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Mouse liver repopulation with hepatocytes generated from human fibroblasts
Human induced pluripotent stem cells (iPSCs) promise to revolutionize research and therapy of liver diseases by providing a source of hepatocytes for autologous cell therapy and disease modeling. However, despite progress in advancing the differentiation of iPSCs into hepatocytes (iPSC-Heps) in vitr...
Autores principales: | Zhu, Saiyong, Rezvani, Milad, Harbell, Jack, Mattis, Aras N., Wolfe, Alan R., Benet, Leslie Z., Willenbring, Holger, Ding, Sheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161230/ https://www.ncbi.nlm.nih.gov/pubmed/24572354 http://dx.doi.org/10.1038/nature13020 |
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