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Efficient Editing of Malaria Parasite Genome Using the CRISPR/Cas9 System

Malaria parasites are unicellular organisms residing inside the red blood cells, and current methods for editing the parasite genes have been inefficient. The CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats and Cas9 endonuclease-mediated genome editing) system is a new powerfu...

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Detalles Bibliográficos
Autores principales: Zhang, Cui, Xiao, Bo, Jiang, Yuanyuan, Zhao, Yihua, Li, Zhenkui, Gao, Han, Ling, Yuan, Wei, Jun, Li, Shaoneng, Lu, Mingke, Su, Xin-zhuan, Cui, Huiting, Yuan, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161241/
https://www.ncbi.nlm.nih.gov/pubmed/24987097
http://dx.doi.org/10.1128/mBio.01414-14