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The Proteasome-Ubiquitin System Is Required for Efficient Killing of Intracellular Streptococcus pneumoniae by Brain Endothelial Cells

Streptococcus pneumoniae (pneumococcus) is a Gram-positive bacterium that causes serious invasive diseases, such as pneumonia, bacteremia, and meningitis, with high morbidity and mortality throughout the world. Before causing invasive disease, S. pneumoniae encounters cellular barriers, which are of...

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Detalles Bibliográficos
Autores principales: Iovino, Federico, Gradstedt, Henrik, Bijlsma, Jetta J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161243/
https://www.ncbi.nlm.nih.gov/pubmed/24987087
http://dx.doi.org/10.1128/mBio.00984-14