Cargando…
Promiscuous and Adaptable Enzymes Fill “Holes” in the Tetrahydrofolate Pathway in Chlamydia Species
Folates are tripartite molecules comprising pterin, para-aminobenzoate (PABA), and glutamate moieties, which are essential cofactors involved in DNA and amino acid synthesis. The obligately intracellular Chlamydia species have lost several biosynthetic pathways for essential nutrients which they can...
Autores principales: | Adams, Nancy E., Thiaville, Jennifer J., Proestos, James, Juárez-Vázquez, Ana L., McCoy, Andrea J., Barona-Gómez, Francisco, Iwata-Reuyl, Dirk, de Crécy-Lagard, Valérie, Maurelli, Anthony T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161248/ https://www.ncbi.nlm.nih.gov/pubmed/25006229 http://dx.doi.org/10.1128/mBio.01378-14 |
Ejemplares similares
-
Diversity of the biosynthesis pathway for threonylcarbamoyladenosine (t(6)A), a universal modification of tRNA
por: Thiaville, Patrick C, et al.
Publicado: (2015) -
Variations in metabolic pathways create challenges for automated metabolic reconstructions: Examples from the tetrahydrofolate synthesis pathway
por: de Crécy-Lagard, Valérie
Publicado: (2014) -
The emerging role of complex modifications of tRNA(Lys)(UUU) in signaling pathways
por: Thiaville, Patrick C., et al.
Publicado: (2015) -
QueF-Like, a Non-Homologous Archaeosine Synthase from the Crenarchaeota
por: Bon Ramos, Adriana, et al.
Publicado: (2017) -
Comparative Genomics Guided
Discovery of Two Missing
Archaeal Enzyme Families Involved in the Biosynthesis of the Pterin
Moiety of Tetrahydromethanopterin and Tetrahydrofolate
por: Crécy-Lagard, Valérie de, et al.
Publicado: (2012)