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STAT5 is critical in Dendritic Cells for development of T(H)2- but not T(H)1-dependent Immunity

Dendritic cells (DCs) are a critical player in immune responses, linking innate and adaptive immunity. We show here that DC-specific deletion of the STAT5 was not critical for development, but was required for type-2, but not type-1, allergic responses in both the skin and lung. Loss of STAT5 in DCs...

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Detalles Bibliográficos
Autores principales: Bell, Bryan D., Kitajima, Masayuki, Larson, Ryan P., Stoklasek, Thomas A., Dang, Kristen, Sakamoto, Kazuhito, Wagner, Kay-Uwe, Reizis, Boris, Hennighausen, Lothar, Ziegler, Steven F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161284/
https://www.ncbi.nlm.nih.gov/pubmed/23435120
http://dx.doi.org/10.1038/ni.2541