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STAT5 is critical in Dendritic Cells for development of T(H)2- but not T(H)1-dependent Immunity
Dendritic cells (DCs) are a critical player in immune responses, linking innate and adaptive immunity. We show here that DC-specific deletion of the STAT5 was not critical for development, but was required for type-2, but not type-1, allergic responses in both the skin and lung. Loss of STAT5 in DCs...
Autores principales: | Bell, Bryan D., Kitajima, Masayuki, Larson, Ryan P., Stoklasek, Thomas A., Dang, Kristen, Sakamoto, Kazuhito, Wagner, Kay-Uwe, Reizis, Boris, Hennighausen, Lothar, Ziegler, Steven F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161284/ https://www.ncbi.nlm.nih.gov/pubmed/23435120 http://dx.doi.org/10.1038/ni.2541 |
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