Principal Component Analysis Characterizes Shared Pathogenetics from Genome-Wide Association Studies

Genome-wide association studies (GWASs) have recently revealed many genetic associations that are shared between different diseases. We propose a method, disPCA, for genome-wide characterization of shared and distinct risk factors between and within disease classes. It flips the conventional GWAS pa...

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Detalles Bibliográficos
Autores principales: Chang, Diana, Keinan, Alon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161298/
https://www.ncbi.nlm.nih.gov/pubmed/25211452
http://dx.doi.org/10.1371/journal.pcbi.1003820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161298/
https://www.ncbi.nlm.nih.gov/pubmed/25211452
http://dx.doi.org/10.1371/journal.pcbi.1003820

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