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Principal Component Analysis Characterizes Shared Pathogenetics from Genome-Wide Association Studies
Genome-wide association studies (GWASs) have recently revealed many genetic associations that are shared between different diseases. We propose a method, disPCA, for genome-wide characterization of shared and distinct risk factors between and within disease classes. It flips the conventional GWAS pa...
Autores principales: | Chang, Diana, Keinan, Alon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161298/ https://www.ncbi.nlm.nih.gov/pubmed/25211452 http://dx.doi.org/10.1371/journal.pcbi.1003820 |
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