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Targeted H3R26 Deimination Specifically Facilitates Estrogen Receptor Binding by Modifying Nucleosome Structure

Transcription factor binding to DNA in vivo causes the recruitment of chromatin modifiers that can cause changes in chromatin structure, including the modification of histone tails. We previously showed that estrogen receptor (ER) target gene activation is facilitated by peptidylarginine deiminase 2...

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Detalles Bibliográficos
Autores principales: Guertin, Michael J., Zhang, Xuesen, Anguish, Lynne, Kim, Sohyoung, Varticovski, Lyuba, Lis, John T., Hager, Gordon L., Coonrod, Scott A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161307/
https://www.ncbi.nlm.nih.gov/pubmed/25211228
http://dx.doi.org/10.1371/journal.pgen.1004613