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IL-10 and NOS2 Modulate Antigen-Specific Reactivity and Nerve Infiltration by T Cells in Experimental Leprosy
BACKGROUND: Although immunopathology dictates clinical outcome in leprosy, the dynamics of early and chronic infection are poorly defined. In the tuberculoid region of the spectrum, Mycobacterium leprae growth is restricted yet a severe granulomatous lesion can occur. The evolution and maintenance o...
Autores principales: | Hagge, Deanna A., Scollard, David M., Ray, Nashone A., Marks, Vilma T., Deming, Angelina T., Spencer, John S., Adams, Linda B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161319/ https://www.ncbi.nlm.nih.gov/pubmed/25210773 http://dx.doi.org/10.1371/journal.pntd.0003149 |
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