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Unkempt Is Negatively Regulated by mTOR and Uncouples Neuronal Differentiation from Growth Control

Neuronal differentiation is exquisitely controlled both spatially and temporally during nervous system development. Defects in the spatiotemporal control of neurogenesis cause incorrect formation of neural networks and lead to neurological disorders such as epilepsy and autism. The mTOR kinase integ...

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Detalles Bibliográficos
Autores principales: Avet-Rochex, Amélie, Carvajal, Nancy, Christoforou, Christina P., Yeung, Kelvin, Maierbrugger, Katja T., Hobbs, Carl, Lalli, Giovanna, Cagin, Umut, Plachot, Cedric, McNeill, Helen, Bateman, Joseph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161320/
https://www.ncbi.nlm.nih.gov/pubmed/25210733
http://dx.doi.org/10.1371/journal.pgen.1004624