Cargando…

Cleavage Specificity Analysis of Six Type II Transmembrane Serine Proteases (TTSPs) Using PICS with Proteome-Derived Peptide Libraries

BACKGROUND: Type II transmembrane serine proteases (TTSPs) are a family of cell membrane tethered serine proteases with unclear roles as their cleavage site specificities and substrate degradomes have not been fully elucidated. Indeed just 52 cleavage sites are annotated in MEROPS, the database of p...

Descripción completa

Detalles Bibliográficos
Autores principales: Barré, Olivier, Dufour, Antoine, Eckhard, Ulrich, Kappelhoff, Reinhild, Béliveau, François, Leduc, Richard, Overall, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161349/
https://www.ncbi.nlm.nih.gov/pubmed/25211023
http://dx.doi.org/10.1371/journal.pone.0105984