High-Throughput Bead-Based Identification of Structure-Switching Aptamer Beacons

We describe a new platform to identify structure-switching DNA beacon aptamers, which detect small molecules in a specific manner. By clonally amplifying a DNA library designed to fluoresce in response to binding events onto microbeads, aptamer beacons can be selected by stringent fluorescence-assis...

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Detalles Bibliográficos
Autores principales: Trevino, Simon G, Levy, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2014
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161366/
https://www.ncbi.nlm.nih.gov/pubmed/25056925
http://dx.doi.org/10.1002/cbic.201402037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161366/
https://www.ncbi.nlm.nih.gov/pubmed/25056925
http://dx.doi.org/10.1002/cbic.201402037

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