Improved Derivation Efficiency and Pluripotency of Stem Cells from the Refractory Inbred C57BL/6 Mouse Strain by Small Molecules

The ability of small molecules to maintain self-renewal and to inhibit differentiation of pluripotent stem cells has been well-demonstrated. Two widely used molecules are PD 98059 (PD), an inhibitor of extracellular-signal-regulated kinase 1 (ERK), and SC1 (Pluripotin), which inhibits the RasGAP and...

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Detalles Bibliográficos
Autores principales: Lin, Chih-Jen, Amano, Tomokazu, Tang, Yong, Tian, Xiuchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161378/
https://www.ncbi.nlm.nih.gov/pubmed/25211343
http://dx.doi.org/10.1371/journal.pone.0106916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161378/
https://www.ncbi.nlm.nih.gov/pubmed/25211343
http://dx.doi.org/10.1371/journal.pone.0106916

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