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In Vitro Surfactant and Perfluorocarbon Aerosol Deposition in a Neonatal Physical Model of the Upper Conducting Airways

OBJECTIVE: Aerosol delivery holds potential to release surfactant or perfluorocarbon (PFC) to the lungs of neonates with respiratory distress syndrome with minimal airway manipulation. Nevertheless, lung deposition in neonates tends to be very low due to extremely low lung volumes, narrow airways an...

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Detalles Bibliográficos
Autores principales: Goikoetxea, Estibalitz, Murgia, Xabier, Serna-Grande, Pablo, Valls-i-Soler, Adolf, Rey-Santano, Carmen, Rivas, Alejandro, Antón, Raúl, Basterretxea, Francisco J., Miñambres, Lorena, Méndez, Estíbaliz, Lopez-Arraiza, Alberto, Larrabe-Barrena, Juan Luis, Gomez-Solaetxe, Miguel Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161382/
https://www.ncbi.nlm.nih.gov/pubmed/25211475
http://dx.doi.org/10.1371/journal.pone.0106835