Cargando…

Arhgap28 Is a RhoGAP that Inactivates RhoA and Downregulates Stress Fibers

The small GTPase RhoA is a major regulator of actin reorganization during the formation of stress fibers; thus identifying molecules that regulate Rho activity is necessary for a complete understanding of the mechanisms that determine cell contractility. Here, we have identified Arhgap28 as a Rho GT...

Descripción completa

Detalles Bibliográficos
Autores principales: Yeung, Ching-Yan Chloé, Taylor, Susan H., Garva, Richa, Holmes, David F., Zeef, Leo A., Soininen, Raija, Boot-Handford, Raymond P., Kadler, Karl E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161385/
https://www.ncbi.nlm.nih.gov/pubmed/25211221
http://dx.doi.org/10.1371/journal.pone.0107036