Structural Basis for Cytochrome c Y67H Mutant to Function as a Peroxidase

The catalytic activity of cytochrome c (cyt c) to peroxidize cardiolipin to its oxidized form is required for the release of pro-apoptotic factors from mitochondria, and for execution of the subsequent apoptotic steps. However, the structural basis for this peroxidation reaction remains unclear. In...

Descripción completa

Detalles Bibliográficos
Autores principales: Lan, Wenxian, Wang, Zhonghua, Yang, Zhongzheng, Ying, Tianlei, Zhang, Xu, Tan, Xiangshi, Liu, Maili, Cao, Chunyang, Huang, Zhong-Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161393/
https://www.ncbi.nlm.nih.gov/pubmed/25210769
http://dx.doi.org/10.1371/journal.pone.0107305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161393/
https://www.ncbi.nlm.nih.gov/pubmed/25210769
http://dx.doi.org/10.1371/journal.pone.0107305

Ejemplares similares