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Structural Basis for Cytochrome c Y67H Mutant to Function as a Peroxidase

The catalytic activity of cytochrome c (cyt c) to peroxidize cardiolipin to its oxidized form is required for the release of pro-apoptotic factors from mitochondria, and for execution of the subsequent apoptotic steps. However, the structural basis for this peroxidation reaction remains unclear. In...

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Detalles Bibliográficos
Autores principales:	Lan, Wenxian, Wang, Zhonghua, Yang, Zhongzheng, Ying, Tianlei, Zhang, Xu, Tan, Xiangshi, Liu, Maili, Cao, Chunyang, Huang, Zhong-Xian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161393/ https://www.ncbi.nlm.nih.gov/pubmed/25210769 http://dx.doi.org/10.1371/journal.pone.0107305

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