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The TIR-Domain Containing Adaptor TRAM Is Required for TLR7 Mediated RANTES Production

Toll-like receptor 7 (TLR7) plays a vital role in the immune response to ssRNA viruses such as human rhinovirus (HRV) and Influenza, against which there are currently no treatments or vaccines with long term efficacy available. Clearly, a more comprehensive understanding of the TLR7 signaling axis w...

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Detalles Bibliográficos
Autores principales: Shevlin, Enda, Miggin, Sinéad M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161432/
https://www.ncbi.nlm.nih.gov/pubmed/25211222
http://dx.doi.org/10.1371/journal.pone.0107141