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Strong Epistatic Selection on the RNA Secondary Structure of HIV

A key question in evolutionary genomics is how populations navigate the adaptive landscape in the presence of epistasis, or interactions among loci. This problem can be directly addressed by studying the evolution of RNA secondary structures, for which there is constraint to maintain pairing between...

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Detalles Bibliográficos
Autor principal: Assis, Raquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161434/
https://www.ncbi.nlm.nih.gov/pubmed/25210786
http://dx.doi.org/10.1371/journal.ppat.1004363