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Strong Epistatic Selection on the RNA Secondary Structure of HIV
A key question in evolutionary genomics is how populations navigate the adaptive landscape in the presence of epistasis, or interactions among loci. This problem can be directly addressed by studying the evolution of RNA secondary structures, for which there is constraint to maintain pairing between...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161434/ https://www.ncbi.nlm.nih.gov/pubmed/25210786 http://dx.doi.org/10.1371/journal.ppat.1004363 |