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MGMT Promoter Methylation Correlates with an Overall Survival Benefit in Chinese High-Grade Glioblastoma Patients Treated with Radiotherapy and Alkylating Agent-Based Chemotherapy: A Single-Institution Study

Promoter methylation of the O(6)-methylguanine-DNA-methyltransferase (MGMT) gene has been considered a prognostic marker and has become more important in the treatment of glioblastoma. However, reports on the correlation between MGMT and clinical outcomes in Chinese glioblastoma patients are very sc...

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Detalles Bibliográficos
Autores principales: Shen, Dong, Liu, Tao, Lin, Qingfen, Lu, Xiangdong, Wang, Qiong, Lin, Feng, Mao, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161443/
https://www.ncbi.nlm.nih.gov/pubmed/25211033
http://dx.doi.org/10.1371/journal.pone.0107558