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SERCaMP: a carboxy-terminal protein modification that enables monitoring of ER calcium homeostasis

Endoplasmic reticulum (ER) calcium homeostasis is disrupted in diverse pathologies, including neurodegeneration, cardiovascular diseases, and diabetes. Temporally defining calcium dysregulation during disease progression, however, has been challenging. Here we describe secreted ER calcium-monitoring...

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Detalles Bibliográficos
Autores principales: Henderson, Mark J., Wires, Emily S., Trychta, Kathleen A., Richie, Christopher T., Harvey, Brandon K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161517/
https://www.ncbi.nlm.nih.gov/pubmed/25031430
http://dx.doi.org/10.1091/mbc.E14-06-1141