Prognostic prediction of glioblastoma by quantitative assessment of the methylation status of the entire MGMT promoter region

BACKGROUND: O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation is reported to be a prognostic and predictive factor of alkylating chemotherapy for glioblastoma patients. Methylation specific PCR (MSP) has been most commonly used when the methylation status of MGMT is assessed. Howeve...

Descripción completa

Detalles Bibliográficos
Autores principales: Kanemoto, Manabu, Shirahata, Mitsuaki, Nakauma, Akiyo, Nakanishi, Katsumi, Taniguchi, Kazuya, Kukita, Yoji, Arakawa, Yoshiki, Miyamoto, Susumu, Kato, Kikuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161852/
https://www.ncbi.nlm.nih.gov/pubmed/25175833
http://dx.doi.org/10.1186/1471-2407-14-641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161852/
https://www.ncbi.nlm.nih.gov/pubmed/25175833
http://dx.doi.org/10.1186/1471-2407-14-641

Ejemplares similares