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Pichia pastoris Aft1 - a novel transcription factor, enhancing recombinant protein secretion

BACKGROUND: The methylotrophic yeast Pichia pastoris is frequently used for the production of recombinant proteins. However, expression levels can vary depending on the target protein. Allowing for simultaneous regulation of many genes, which may elicit a desired phenotype like increased protein pro...

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Detalles Bibliográficos
Autores principales: Ruth, Claudia, Buchetics, Markus, Vidimce, Viktorija, Kotz, Daniela, Naschberger, Stefan, Mattanovich, Diethard, Pichler, Harald, Gasser, Brigitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161868/
https://www.ncbi.nlm.nih.gov/pubmed/25205197
http://dx.doi.org/10.1186/s12934-014-0120-5