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Orders of Magnitude Extension of the Effective Dynamic Range of TDC-Based TOFMS Data Through Maximum Likelihood Estimation

In a recent article, we derived a probability distribution that was shown to closely approximate that of the data produced by liquid chromatography time-of-flight mass spectrometry (LC/TOFMS) instruments employing time-to-digital converters (TDCs) as part of their detection system. The approach of f...

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Detalles Bibliográficos
Autores principales: Ipsen, Andreas, Ebbels, Timothy M. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161928/
https://www.ncbi.nlm.nih.gov/pubmed/25049115
http://dx.doi.org/10.1007/s13361-014-0961-5