Notoginsenoside R1 increases neuronal excitability and ameliorates synaptic and memory dysfunction following amyloid elevation

Neurodegeneration and synaptic dysfunction observed in Alzheimer's disease (AD) have been associated with progressive decrease in neuronal activity. Here, we investigated the effects of Notoginsenoside R1 (NTR1), a major saponin isolated from Panax notoginseng, on neuronal excitability and asse...

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Detalles Bibliográficos
Autores principales: Yan, Shijun, Li, Zhi, Li, Hang, Arancio, Ottavio, Zhang, Wensheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161968/
https://www.ncbi.nlm.nih.gov/pubmed/25213453
http://dx.doi.org/10.1038/srep06352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161968/
https://www.ncbi.nlm.nih.gov/pubmed/25213453
http://dx.doi.org/10.1038/srep06352

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