NVP-BEZ-235 enhances radiosensitization via blockade of the PI3K/mTOR pathway in cisplatin-resistant non-small cell lung carcinoma

INTRODUCTION: Most drug resistant cancer cells also develop resistance to radiation therapy. In this study, we hypothesized that the dual inhibitor of phosphatidylinositol-3 kinase/mammalian target of rapamycin, NVP-BEZ-235, could potentially enhance radiosensitization in cisplatin-resistance (CDDP-...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Kwang Woon, Myers, Carey J., Jung, Dae Kwang, Lu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162139/
https://www.ncbi.nlm.nih.gov/pubmed/25221647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162139/
https://www.ncbi.nlm.nih.gov/pubmed/25221647

Ejemplares similares