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Proteomic Analysis Reveals Age-related Changes in Tendon Matrix Composition, with Age- and Injury-specific Matrix Fragmentation

Energy storing tendons, such as the human Achilles and equine superficial digital flexor tendon (SDFT), are highly prone to injury, the incidence of which increases with aging. The cellular and molecular mechanisms that result in increased injury in aged tendons are not well established but are thou...

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Detalles Bibliográficos
Autores principales: Peffers, Mandy J., Thorpe, Chavaunne T., Collins, John A., Eong, Robin, Wei, Timothy K. J., Screen, Hazel R. C., Clegg, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162187/
https://www.ncbi.nlm.nih.gov/pubmed/25077967
http://dx.doi.org/10.1074/jbc.M114.566554