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Genome-wide analysis of histone modifications in latently HIV-1 infected T cells

OBJECTIVES: The transcriptional silencing of HIV type 1 (HIV-1) provirus in latently infected cells is a major hurdle on the pathway to HIV-1 elimination. The epigenetic mechanisms established by histone modifications may affect the transcriptional silencing of HIV-1 and viral latency. A systematic...

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Detalles Bibliográficos
Autores principales: Park, Jihwan, Lim, Chae Hyun, Ham, Seokjin, Kim, Sung Soon, Choi, Byeong-Sun, Roh, Tae-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162335/
https://www.ncbi.nlm.nih.gov/pubmed/24762674
http://dx.doi.org/10.1097/QAD.0000000000000309