Cargando…

Fingolimod for the treatment of neurological diseases—state of play and future perspectives

Sphingolipids are a fascinating class of signaling molecules derived from the membrane lipid sphingomyelin. They show abundant expression in the brain. Complex sphingolipids such as glycosphingolipids (gangliosides and cerebrosides) regulate vesicular transport and lysosomal degradation and their dy...

Descripción completa

Detalles Bibliográficos
Autores principales: Brunkhorst, Robert, Vutukuri, Rajkumar, Pfeilschifter, Waltraud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162362/
https://www.ncbi.nlm.nih.gov/pubmed/25309325
http://dx.doi.org/10.3389/fncel.2014.00283