Exosomal HIF1α supports invasive potential of nasopharyngeal carcinoma-associated LMP1-positive exosomes

It has emerged recently that exosomes are potential carriers of pro-tumorigenic factors that participate in oncogenesis. However, whether oncogenic transcription factors are transduced by exosomes is unknown. Hypoxia-inducible factor-1α (HIF1α) transcriptionally regulates numerous key aspects of tum...

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Detalles Bibliográficos
Autores principales: Aga, M, Bentz, G L, Raffa, S, Torrisi, M R, Kondo, S, Wakisaka, N, Yoshizaki, T, Pagano, J S, Shackelford, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162459/
https://www.ncbi.nlm.nih.gov/pubmed/24662828
http://dx.doi.org/10.1038/onc.2014.66

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162459/
https://www.ncbi.nlm.nih.gov/pubmed/24662828
http://dx.doi.org/10.1038/onc.2014.66

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