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Exosomal HIF1α supports invasive potential of nasopharyngeal carcinoma-associated LMP1-positive exosomes

It has emerged recently that exosomes are potential carriers of pro-tumorigenic factors that participate in oncogenesis. However, whether oncogenic transcription factors are transduced by exosomes is unknown. Hypoxia-inducible factor-1α (HIF1α) transcriptionally regulates numerous key aspects of tum...

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Detalles Bibliográficos
Autores principales:	Aga, M, Bentz, G L, Raffa, S, Torrisi, M R, Kondo, S, Wakisaka, N, Yoshizaki, T, Pagano, J S, Shackelford, J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162459/ https://www.ncbi.nlm.nih.gov/pubmed/24662828 http://dx.doi.org/10.1038/onc.2014.66

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