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Autoreactivity to Glucose Regulated Protein 78 Links Emphysema and Osteoporosis in Smokers

RATIONALE: Emphysema and osteoporosis are epidemiologically associated diseases of cigarette smokers. The causal mechanism(s) linking these illnesses is unknown. We hypothesized autoimmune responses may be involved in both disorders. OBJECTIVES: To discover an antigen-specific autoimmune response as...

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Detalles Bibliográficos
Autores principales: Bon, Jessica, Kahloon, Rehan, Zhang, Yingze, Xue, Jianmin, Fuhrman, Carl R., Tan, Jiangning, Burger, Mathew, Kass, Daniel J., Csizmadia, Eva, Otterbein, Leo, Chandra, Divay, Bhargava, Arpit, Pilewski, Joseph M., Roodman, G. David, Sciurba, Frank C., Duncan, Steven R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162538/
https://www.ncbi.nlm.nih.gov/pubmed/25216103
http://dx.doi.org/10.1371/journal.pone.0105066