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Diosgenin from Dioscorea bulbifera: Novel Hit for Treatment of Type II Diabetes Mellitus with Inhibitory Activity against α-Amylase and α-Glucosidase

Diabetes mellitus is a multifactorial metabolic disease characterized by post-prandial hyperglycemia (PPHG). α-amylase and α-glucosidase inhibitors aim to explore novel therapeutic agents. Herein we report the promises of Dioscorea bulbifera and its bioactive principle, diosgenin as novel α-amylase...

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Detalles Bibliográficos
Autores principales: Ghosh, Sougata, More, Piyush, Derle, Abhishek, Patil, Ajay B., Markad, Pramod, Asok, Adersh, Kumbhar, Navanath, Shaikh, Mahemud L., Ramanamurthy, Boppana, Shinde, Vaishali S., Dhavale, Dilip D., Chopade, Balu A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162539/
https://www.ncbi.nlm.nih.gov/pubmed/25216353
http://dx.doi.org/10.1371/journal.pone.0106039