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Induction of Body Weight Loss through RNAi-Knockdown of APOBEC1 Gene Expression in Transgenic Rabbits

In the search of new strategies to fight against obesity, we targeted a gene pathway involved in energy uptake. We have thus investigated the APOB mRNA editing protein (APOBEC1) gene pathway that is involved in fat absorption in the intestine. The APOB gene encodes two proteins, APOB100 and APOB48,...

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Detalles Bibliográficos
Autores principales: Jolivet, Geneviève, Braud, Sandrine, DaSilva, Bruno, Passet, Bruno, Harscoët, Erwana, Viglietta, Céline, Gautier, Thomas, Lagrost, Laurent, Daniel-Carlier, Nathalie, Houdebine, Louis-Marie, Harosh, Itzik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162549/
https://www.ncbi.nlm.nih.gov/pubmed/25216115
http://dx.doi.org/10.1371/journal.pone.0106655