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Cancer Cells Differentially Activate and Thrive on De Novo Lipid Synthesis Pathways in a Low-Lipid Environment

Increased lipogenesis is a hallmark of a wide variety of cancers and is under intense investigation as potential antineoplastic target. Although brisk lipogenesis is observed in the presence of exogenous lipids, evidence is mounting that these lipids may adversely affect the efficacy of inhibitors o...

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Detalles Bibliográficos
Autores principales: Daniëls, Veerle W., Smans, Karine, Royaux, Ines, Chypre, Melanie, Swinnen, Johannes V., Zaidi, Nousheen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162556/
https://www.ncbi.nlm.nih.gov/pubmed/25215509
http://dx.doi.org/10.1371/journal.pone.0106913