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Impact of EGFR Mutation Detection Methods on the Efficacy of Erlotinib in Patients with Advanced EGFR-Wild Type Lung Adenocarcinoma

INTRODUCTION: Methods used for epidermal growth factor receptor (EGFR) mutation testing vary widely. The impact of detection methods on the rates of response to EGFR-tyrosine kinase inhibitors (TKIs) in EGFR-wild type (wt) lung adenocarcinoma patients is unknown. METHODS: We recruited the Group-I pa...

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Detalles Bibliográficos
Autores principales: Tseng, Jeng-Sen, Wang, Chih-Liang, Huang, Ming-Shyan, Chen, Chung-Yu, Chang, Cheng-Yu, Yang, Tsung-Ying, Tsai, Chi-Ren, Chen, Kun-Chieh, Hsu, Kuo-Hsuan, Tsai, Meen-Hsin, Yu, Sung-Liang, Su, Kang-Yi, Wu, Chih-Wei, Yang, Cheng-Ta, Chen, Yuh-Min, Chang, Gee-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162576/
https://www.ncbi.nlm.nih.gov/pubmed/25215536
http://dx.doi.org/10.1371/journal.pone.0107160