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Foramen Ovale Closure Is a Process of Endothelial-to-Mesenchymal Transition Leading to Fibrosis

Patent foramen ovale (PFO) is an atrial septal deformity present in around 25% of the general population. PFO is associated with major causes of morbidity, including stroke and migraine. PFO appears to be heritable but genes involved in the closure of foramen ovale have not been identified. The aim...

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Detalles Bibliográficos
Autores principales: Elliott, Graeme C., Gurtu, Rockesh, McCollum, Charles, Newman, William G., Wang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162597/
https://www.ncbi.nlm.nih.gov/pubmed/25215881
http://dx.doi.org/10.1371/journal.pone.0107175