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IL-1 Signaling in Obesity-Induced Hepatic Lipogenesis and Steatosis

Non-alcoholic fatty liver disease is prevalent in human obesity and type 2 diabetes, and is characterized by increases in both hepatic triglyceride accumulation (denoted as steatosis) and expression of pro-inflammatory cytokines such as IL-1β. We report here that the development of hepatic steatosis...

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Detalles Bibliográficos
Autores principales: Negrin, Kimberly A., Roth Flach, Rachel J., DiStefano, Marina T., Matevossian, Anouch, Friedline, Randall H., Jung, DaeYoung, Kim, Jason K., Czech, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162604/
https://www.ncbi.nlm.nih.gov/pubmed/25216251
http://dx.doi.org/10.1371/journal.pone.0107265