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IL-1 Signaling in Obesity-Induced Hepatic Lipogenesis and Steatosis
Non-alcoholic fatty liver disease is prevalent in human obesity and type 2 diabetes, and is characterized by increases in both hepatic triglyceride accumulation (denoted as steatosis) and expression of pro-inflammatory cytokines such as IL-1β. We report here that the development of hepatic steatosis...
Autores principales: | Negrin, Kimberly A., Roth Flach, Rachel J., DiStefano, Marina T., Matevossian, Anouch, Friedline, Randall H., Jung, DaeYoung, Kim, Jason K., Czech, Michael P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162604/ https://www.ncbi.nlm.nih.gov/pubmed/25216251 http://dx.doi.org/10.1371/journal.pone.0107265 |
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